Fig. 6
The tumorigenesis of RCC cells transfected with MPC1 in mice. a Western blotting of MPC1 in Scramble (shCtrl) and shMPC1 transfected 786-O cells. b Subcutaneous tumor formation on day 30 in NOD-SCID mice by Mock, OE-MPC1, shCtrl, and shMPC1 786-O cells (1 × 106 cells/mice). c and d The weight (c) and volume (d) of tumors formed by Mock, OE-MPC1, shCtrl, and shMPC1 786-O cells in mice, **P < 0.01; *P < 0.05. e Representative IHC staining for MPC1, MMP7, and HIF1α in tumors formed by Mock and OE-MPC1 786-O cells. Scale bar = 20 μm
