Table 3 Univariate and multivariate analysis of overall survival (Cox proportional hazards model)

From: Cytoplasmic expression of epithelial cell transforming sequence 2 in lung adenocarcinoma and its implications for malignant progression

Factors

Univariate

Multivariate

HR

95% CI

P-value

HR

95% CI

P-value

Age, years (≥60 vs <60)

1.088

0.546–2.169

0.81

   

Gender (male vs female)

0.398

0.221–0.717

0.002

0.94

0.470–1.881

0.862

Lymphatic permeation (− vs +)

0.199

0.112–0.351

 < 0.001

0.4

0.194–0.823

0.013

Vascular invasion (− vs +)

0.186

0.106–0.328

 < 0.001

0.577

0.280–1.188

0.136

Pleural invasion (0 vs 1, 2, 3)

0.218

0.126–0.375

 < 0.001

0.573

0.297–1.107

0.097

Pathological stage (stage 0, 1 vs other)

0.22

0.126–0.382

 < 0.001

1.04

0.510–2.121

0.915

Cytoplasmic ECT2 expression (−) vs (+)

5.396

2.836–10.267

 < 0.001

2.584

1.124–5.939

0.025

  1. Bold font indicates statistical significance
  2. HR hazard ratio, 95% CI 95% confidence interval
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