Fig. 2 | Laboratory Investigation

Fig. 2

From: MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

Fig. 2

Approaches based on Isothermal amplification. a Schematic representation of the exponential amplification reaction using let-7a miRNA as the amplification template. P indicates a phosphate group (adapted from ref. [64]). b Illustration of the LAMP reaction initiated by the target miRNA let-7a. Reproduced with permission from ref. [65]. c Illustration of the target-primed branched rolling circle amplification reaction. Reproduced with permission from ref. [68]

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