Fig. 1 | Laboratory Investigation

Fig. 1

From: MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type

Fig. 1

a. Western blot analysis of total cell lysates of MEF2B in MEF2B-deficient cell lines (OCI-LY-3, HBL-1, and SU-DHL-2) and MEF2B-expressing cell lines (SU-DHL-4, SU-DHL-5, and SU-DHL-6) demonstrates the expression of BCL6, CD10, and phosphorylation of ERK1/2 in the MEF2B-expressing cell lines. Actin was used as an internal control for loading and transfer. Data are representative of three independent experiments. b Time-course experiment demonstrates the growth rate of MEF2B-deficient cell lines (OC-LY-3, HBL-1, and SU-DHL-2) and MEF2B-expressing cell lines (SU-DHL-4, SU-DHL-5, and SU-DHL-6). MTT assay demonstrated the growth rate of MEF2B-deficient (OCI-LY-3, HBL-1, and SU-DHL-2) and MEF2B-expressing cell lines (SU-DHL-4, SU-DHL-5, and SU-DHL-6) cell lines. The values are expressed as the means ± SD of three independent experiments performed in duplicate

Back to article page