Fig. 3 | Laboratory Investigation

Fig. 3

From: MEF2B is a member of the BCL6 gene transcriptional complex and induces its expression in diffuse large B-cell lymphoma of the germinal center B-cell-like type

Fig. 3

a Cell cycle analysis demonstrates G1, S, and G2 phase in control (Ctr) and siRNA-transfected MEF2B-expressing (SU-DHL-4 and SU-DHL-5) cell lines. Cell populations represent each phase of cell cycle for SU-DHL-4 and SU-DHL-5 cell lines before and after the transfection with siRNA specific to MEF2B. b Flow cytometry analysis of apoptosis demonstrates the portion of annexin V-stained cell in SU-DHL-4 and SU-DHL-5 cell lines before and after transfection with siRNA specific to MEF2B for the indicated time periods. Apoptotic cells are represented in the lower right corner. Data are representative of three independent experiments performed separately

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