Fig. 9

Progression of diabetic retinopathy in the Nile rat. In our cohort, 75% of diabetic rats ≥ 24 weeks old had increased acellular capillaries, mean RBG ≥ 128 mg/dL; duration of diabetes ≥ 8 weeks; 17% of diabetic rats ≥ 32 weeks old had lipemia retinalis, mean RBG ≥ 235 mg/dL; duration of diabetes ≥ 24 weeks, 23% of diabetic rats ≥ 45 weeks old had microvascular abnormalities, mean RBG ≥ 277 mg/dL, duration of diabetes ≥ 32 weeks; 3% of diabetic rats ≥ 52 weeks old had localized extensive capillary loss, mean RBG ≥ 237 mg/dL, duration of diabetes ≥ 30 weeks; 7% of diabetic rats ≥ 68 weeks old had proliferative diabetic retinopathy, mean RBG ≥ 448 mg/dL, duration of diabetes ≥ 48 weeks