Fig. 1

A schematic overview of the Cas9 enrichment workflow showing the wet laboratory (a) and informatics steps (b). Cleavage reactions for (+) and (−) strand guide RNAs are performed separately to prevent interference

A schematic overview of the Cas9 enrichment workflow showing the wet laboratory (a) and informatics steps (b). Cleavage reactions for (+) and (−) strand guide RNAs are performed separately to prevent interference