Fig. 4
EMT and TNFAIP2 expression in 16 clinical samples of bladder urothelial cancer peri-platinum treatment. Immunostaining of E-cadherin a and TNFAIP2 b expression in matched bladder urothelial cancer sections obtained before and after CDDP-based chemotherapy. Panels a and b show spaghetti plots of responses on individual immunosignals peri-chemotherapy (red, decreased; green, increased). c The schematic dynamics of E-cadherin and TNFAIP2 expression in matched bladder urothelial cancer sections obtained before and after CDDP-based chemotherapy (green, pre chemotherapy; red, post chemotherapy). d Representative images of TNFAIP2 mRNA expression in a bladder urothelial cancer section obtained after CDDP-based chemotherapy. Each dot shows a single RNA transcript. Spaghetti plots in the right panel show changes in TNFAIP2 mRNA levels peri-chemotherapy (red, decreased; orange, no change; green, increased). P values from the paired t-test
