Fig. 5 | Laboratory Investigation

Fig. 5

From: TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia

Fig. 5

TRPM7 activity inhibition and suppression of TRPM7 expression protect against kidney dysfunction during endotoxemia. Serum creatinine and blood urea nitrogen were measured in animals treated with carvacrol (a, b), AdVshTRPM7 (c, d), or corresponding vehicle. Statistical differences were assessed by two-way analysis of variance (ANOVA) followed by Bonferroni’s post hoc test. *p < 0.05, ***p < 0.001 against Veh/Sal condition. Histogram bars show mean ± SD (N = 6 per group)

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