Table 1 Relationship between TRPV4 intensity and clinicopathological characteristics of OSCC cases.

From: The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation

 

TRPV4 expression

P value

–

Weak

Moderate

Strong

Clinical T stage

 T1

6

2

2

2

0

 

 T2

6

2

2

2

0

 

 T3

14

5

3

4

2

 

 T4

10

5

5

0

0

N.S.a

Histologic grade

 Well

29

10

12

6

1

 

 Moderately

5

2

0

2

1

 

 Poorly

2

2

0

0

0

N.S.a

Lymph node metastasis

 Positive

9

2

6

0

1

 

 Negative

27

12

6

8

1

N.S.a

  1. Clinical T stage; T1 Tumour 2 cm or less in greatest dimension and 5 mm or less depth of invasion, T2 Tumour 2 cm or less in greatest dimension and more than 5 mm depth of invasion or Tumour more than 2 cm but not more than 4 cm in greatest dimension and depth of invasion no more than 10 mm, T3 Tumour more than 2 cm but not more than 4 cm in greatest dimension and depth of invasion more than 10 mm or Tumour more than 4 cm in greatest dimension and not more than 10 mm depth of invasion, T4a (Lip), Tumour invades through cortical bone, inferior alveolar nerve, floor of mouth, or skin (of the chin or the nose), T4a (Oral cavity), Tumour more than 4 cm in greatest dimension and more than 10 mm depth of invasion or tumour invades through the cortical bone of the mandible or maxilla or involves the maxillary sinus, or invades the skin of the face, T4b (Lip and oral cavity), Tumour invades masticator space, pterygoid plates, or skull base, or encases internal carotid artery. Histologic grade (WHO); Grade 1 well differentiated, Grade 2 moderately differentiated, Grade 3 poorly differentiated
  2. aStatistical analyses were performed by Fisher’s exact test
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