Fig. 3: GTSE1 promotes prostate cancer cell proliferation in vitro and in vivo.
From: GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway
A Efficiency of GTSE1 overexpression and knockdown in LNCaP and C4-2 cells, respectively. B, C Cell viability measured by a Cell Counting Kit-8 assay. Colony formation by LNCaP (D) and C4-2 cells (E). The left side contains representative images, and the right side contains quantized results. F EdU staining of LNCaP and C4-2 cells. G Positive regulation of Ki67 by GTSE1 in LNCaP and C4-2 cells. Cell cycle distributions of LNCaP (H) and C4-2 cells (I) evaluated by flow cytometry. The left images are raw data from the flow cytometric analysis, and the right side shows the quantitative analysis results. J, K, Inhibition of the tumorigenicity of C4-2 cells in vivo resulting from GTSE1 knockdown.
