Fig. 5: SNHG5 regulates angiogenesis via miR-26b/CTGF axis.

The cells were treated with miR-26b inhibitor and sh-SNHG5 or sh-VEGFA followed by the detection of cell proliferation a with colony formation assay, cell cycle analysis (b) with FACS, assessment of cell migration (c), and invasion (d) using Transwell assay, and measurement of angiogenesis (e) with endothelial tube formation assay. “*” denotes p < 0.05; “**” denotes p < 0.01; “***” denotes p < 0.001. Data are expressed as the mean ± SD.