Fig. 6: Effects of ethanol feeding on the intestinal permeability.
From: Enhanced alcoholic liver disease in mice with intestine-specific farnesoid X receptor deficiency
a Representative stained images of E-cadherin along the ileal crypt–villus axis (star) from all strains fed either vehicle or ethanol. b Plasma levels of FITC-dextran in vehicle and ethanol-fed mice. Mice (n = 5) were administered FITC-dextran via oral gavage to determine intestinal permeability. Values are presented as mean ± SD. An asterisk (*) indicates statistical significance (p < 0.05) of ethanol treatment compared with vehicle (Veh) control group in the same strain. A hash symbol (#) indicates statistical significance between WT and FXRInt−/− mice (p < 0.05) with the same treatment. The scale bars show 50 μm for ×200 magnification.
