Fig. 4: MiR-185-5p alleviates the degree of endoplasmic reticulum stress in a mouse model of unilateral urethral obstruction.
From: MiR-185-5p ameliorates endoplasmic reticulum stress and renal fibrosis by downregulation of ATF6
a Real-time PCR of miR-185-5p in the kidney of unilateral urethral obstruction (UUO) mice (n = 6 per group). b ATF6 mRNA level in the kidney of UUO mice. c Western blot analysis of ATF6, GRP78, and CHOP proteins in the kidney of UUO mice. d–f Quantification of the gray values of Western blots in (c). Data are presented as the mean ± SD (n = 6) based on one-way ANOVA with Tukey’s test of three independent experiments. **P < 0.01; ***P < 0.001; ****P < 0.0001.
