Table 1 Clinicopathological features of primary lung carcinoma used PDX generation.

From: Gene expression profiles of the original tumors influence the generation of PDX models of lung squamous cell carcinoma

 

Non-engrafting (NEG)

Engrafting (EG)

Total

P value

#Engraftment

28 (54.9%)

23 (45.1%)

51

 

Age, year (Mean ± SD)

69.4 ± 8.8

68.8 ± 8.9

69.2 ± 8.9

P = 0.405

Sex

   

P = 0.135

   Female

13

6

19

 

   Male

15

17

32

 

Smoking history

   

P = 0.510

   No

11

7

18

 

   Yes

17

16

33

 

 Brinkman Index (BI, mean ± SD)

1021.9 ± 589.7

1020.9 ± 589.7

1089.7 ± 500.0

P = 0.223

Pathological subtype

   

P = 0.013

   LUSC

2

8

10

*

   LUAD

25

12

37

 

   Others

1

3

4

 

Pathological stage

   

P = 0.538

   I + II

24

21

45

 

   III + IV

4

2

6

 

Lymphatic permeation

   

P = 0.487

   Negative

24

18

42

 

   Positive

4

5

9

 

Vascular invasion

   

P = 0.137

   Negative

18

10

28

 

   Positive

10

13

23

 
  1. Stage I includes IA and IB, stage II includes IIA and IIB, and stage III includes IIIA and IIIB. Correlation between engraftment and clinicopathological features was analyzed using the chi-squared test. P value *<0.05.
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