Fig. 4: Summary of the results. | Laboratory Investigation

Fig. 4: Summary of the results.

From: An improved assay for detection of theranostic gene translocations and MET exon 14 skipping in thoracic oncology

Fig. 4

A Comparative evaluation of the positive cases retrieved by LD-RT-PCR, by routine analysis and by both for ALK, ROS1, RET translocation, MET exon 14 skipping and in total. B Contingency table used to calculate the performance characteristics of LD-RT-PCR to detect ALK, ROS1, RET translocation and MET exon 14 skipping. C Contingency table used to calculate the performance characteristics of routine analysis to detect ALK, ROS1, RET translocation and MET exon 14 skipping. Se sensitivity, Sp specificity, PPV positive predictive value, NPV negative predictive value, 95% CI 95% confidence interval, LD-RT-PCR ligation-dependent reverse transcription polymerase chain reaction.

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