Fig. 4: Results of Treg cells in wild-type mice and PD-1−/− group after skeletal muscle contusion. | Laboratory Investigation

Fig. 4: Results of Treg cells in wild-type mice and PD-1−/− group after skeletal muscle contusion.

From: Programmed death-1 promotes contused skeletal muscle regeneration by regulating Treg cells and macrophages

Fig. 4

(a) Foxp3 immunofluorescence staining of Treg cell markers. (b) Average positive cells in a single field of view. (c) AREG (specific muscle growth factor secreted by Treg cells) mRNA expression at various time points after skeletal muscle contusion. Data are mean ± SD, n (WT) = 8, n (PD-1−/−) = 6. aCompared with WTcon group or WT1 group, P < 0.05; bCompared with Pcon group or P1 group, P < 0.05; cAt the same time point, the PD-1−/− mice compared with wild-type mice, P < 0.05.

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