Fig. 6: Expression of pro-inflammatory and anti-inflammatory factors in wild-type mice and PD-1−/− mice after skeletal muscle contusion. | Laboratory Investigation

Fig. 6: Expression of pro-inflammatory and anti-inflammatory factors in wild-type mice and PD-1−/− mice after skeletal muscle contusion.

From: Programmed death-1 promotes contused skeletal muscle regeneration by regulating Treg cells and macrophages

Fig. 6

(a) IL-1β mRNA expression at various time points after skeletal muscle contusion. (b) IL-6 mRNA expression at various time points after skeletal muscle contusion (c) TNF-α mRNA expression at various time points after skeletal muscle contusion. (d) Skeletal muscle TGF-β mRNA expression at various time points after skeletal muscle contusion (e) IL-4 mRNA expression at various time points after skeletal muscle contusion. (f) IL-10 mRNA expression at various time points after skeletal muscle contusion. Data are mean ± SD, n (WT) = 8, n (PD-1−/−) = 6. aCompared with WTcon group, P < 0.05; bCompared with Pcon group, P < 0.05; cat the same time point, the PD-1−/− mice compared with wild-type mice, P < 0.05.

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