Fig. 8: Expression of muscle regeneration factors in wild-type mice and PD-1−/− mice after skeletal muscle contusion.

(a) Pax7 mRNA expression at various time points after skeletal muscle contusion. (b) MGF mRNA expression at various time points after skeletal muscle contusion. (c) IGF-1 mRNA expression at various time points after skeletal muscle contusion. (d) MyoD mRNA expression at various time points after skeletal muscle contusion. (e) Myogenin mRNA expression at various time points after skeletal muscle contusion. Data are mean ± SD, n (WT) = 8, n (PD-1−/−) = 6. aCompared with WTcon group, P < 0.05; bCompared with Pcon group, P < 0.05; cat the same time point, the PD-1−/− mice compared with wild-type mice, P < 0.05.