Fig. 2: Choline attenuates cardiac remodeling in abdominal aortic coarctation (AAC) rats. | Laboratory Investigation

Fig. 2: Choline attenuates cardiac remodeling in abdominal aortic coarctation (AAC) rats.

From: Amelioration of circadian disruption and calcium-handling protein defects by choline alleviates cardiac remodeling in abdominal aorta coarctation rats

Fig. 2

a Representative images of cardiac morphology, cardiomyocyte hypertrophy, and collagen deposition. Scale bars = 5 mm (top), 50 μm (middle) and 50 μm (bottom). b, c Area and cross-sectional diameter of cardiomyocytes in the left ventricle; n = 8 rats per group. d Area of cardiac fibrosis stained by Masson’s trichrome; n = 6 rats per group. e, f Ratio of heart weight/body weight (HW/BW) and left ventricular weight (LVW)/BW; n = 8 rats per group. g Mean arterial pressure; n = 8 rats per group. Data are means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001. H&E, hematoxylin and eosin.

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