Fig. 6: miR-155-5p promotes the development of cALL through the CBL/IRF4/CDK6 axis. | Laboratory Investigation

Fig. 6: miR-155-5p promotes the development of cALL through the CBL/IRF4/CDK6 axis.

From: microRNA-155-5p initiates childhood acute lymphoblastic leukemia by regulating the IRF4/CDK6/CBL axis

Fig. 6

A The statistical histogram denoting miR-155-5p expression, as determined by RT-qPCR. B The protein expression levels of CBL, IRF4, and CDK6 as determined by the Western blot assay. C Kaplan–Meier survival curve for the mouse survival rate. D The 697 cell proportion as examined by flow cytometry. E The statistical histogram denoting mouse liver and spleen, and coefficient of liver and spleen. F HE staining for the mouse liver and spleen. *p < 0.05 indicates significant difference between groups (n of mice = 10).

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