Table 2 Engraftments of human 697 cells in NOD/SCID mice.

From: microRNA-155-5p initiates childhood acute lymphoblastic leukemia by regulating the IRF4/CDK6/CBL axis

 

Mice engrafted

Overall survival (%)

Final engraftment level

(hCD19 + E2A/Pbx1 + %, mean ± SD)

Peripheral blood

Bone marrow

Blank

10

100.0%

13.89 3.1.71

10.52 0.1.63

antagomir NC + oe-NC

10

40.0%

30.24 0.2.16

23.52 3.2.98

miR-155-5p antagomir + oe-NC

10

80.0%

13.69 3.1.07

11.01 1.1.52

miR-155-5p antagomir + oe-CDK6

10

30.0%

31.71 1.2.19

24.09 4.2.46

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