Table 3 The depicted confusion matrix illustrates the performance of our proposed diagnostic algorithm to translate measured CD8+ T-cell densities into a respective immune diagnostic category in the validation cohort.

From: Establishing standardized immune phenotyping of metastatic melanoma by digital pathology

Confusion matrix

Pathologist diagnosis

True positives (TP)

True negatives (TN)

False positives (FP)

False negatives (FN)

Sensitivity (Recall)

Specificity

Positive predictive value (Precision)

Desert (n = 10)

Excluded (n = 18)

Inflamed (n = 5)

Predicted

 Desert

10

0

0

10

23

0

0

100%

100%

100%

 Excluded

0

15

0

15

15

0

3

83%

100%

100%

 Inflamed

0

3

5

5

25

3

0

100%

89%

62.5%

  1. Whereas the prediction, sensitivity, and specificity of immune desert tumors was very robust, few excluded tumors were attributed to the inflamed immune diagnostic category.