Fig. 1: Distinct expression profiles and salience of PLCG1 between IDHwt LGG and IM LGG. | Laboratory Investigation

Fig. 1: Distinct expression profiles and salience of PLCG1 between IDHwt LGG and IM LGG.

From: Phospholipase Cγ1 (PLCG1) overexpression is associated with tumor growth and poor survival in IDH wild-type lower-grade gliomas in adult patients

Fig. 1

a Hierarchical cluster analysis of 1183 highly variable genes (rows) in 24 LGG cases (columns). b Kaplan–Meier survival analysis of retrospective follow-up studies of IDHwt LGG patients admitted to Huashan Hospital from 2013–2016 (divided by median PLCG1 expression, p < 0.05). c Kaplan–Meier survival analysis of PLCG1 in IDHwt patients from the CGGA_LGG database (divided by median PLCG1 expression, p < 0.01). d Kaplan–Meier survival analysis of PLCG1 in IDHwt patients from the TCGA_LGG database (divided by median PLCG1 expression, p < 0.0001).

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