Fig. 5: Changes in free and high-glucose INS-1 cells. | Laboratory Investigation

Fig. 5: Changes in free and high-glucose INS-1 cells.

From: SIRT6 regulates SREBP1c-induced glucolipid metabolism in liver and pancreas via the AMPKα-mTORC1 pathway

Fig. 5

a cell viability tested by CCK-8; b and c metabolic enzyme abundance of Gck and Pck1; d–f the abundance of Sirt6, Ampk, and mtor mRNA; g–l levels of SIRT6, p-AMPKα/AMPKα, p-mTOR/mTOR, p-Raptor/Raptor, and Rheb in INS-1 cells. *Compared with the NC group, P < 0.05; #Compared with the ST group, P < 0.05. n = 6 per group.

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