Fig. 2: Spatial distribution of specific m/z species. | Laboratory Investigation

Fig. 2: Spatial distribution of specific m/z species.

From: Simultaneous metabolite MALDI-MSI, whole exome and transcriptome analysis from formalin-fixed paraffin-embedded tissue sections

Fig. 2

By matching the FFPE-HE staining A with the MSI measurement, specific tumor tissue areas can be visualized. The metabolite m/z 148.8547 is exclusively abundant in the tumor stroma B, whereas m/z 152.9452 is clearly overrepresented in tumor cell areas C. The overlay of the two visualizations D shows that the metabolites do not overlap in any area.

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