Fig. 1

Overview of mutations at diagnosis and in remission. a Frequency of mutations identified at diagnosis in ≥4 patients. b Heatmap depicting gene mutations occurring in ≥4 patients. Each column represents one patient. The left panel represents patients without, and the right panel shows patients with persisting mutations in remission. c Allele frequencies of mutations in commonly mutated genes in paired diagnosis and remission samples from individual patients. Persisting mutations are shown in red, and mutations undetectable in remission in gray