Fig. 2

Molecular function ontology classes of genes on 1q upregulated in dup(1q)-positive cases. a In the HeH cases, 28 of the 46 upregulated genes on 1q had defined molecular functions, comprising seven classes. b In the (1;19) cases, 44 of the 76 overexpressed genes on 1q had defined molecular functions, comprising five ontology classes. Antioxidant activity (GO:0016209); binding (GO:0005488); catalytic activity (GO:0003824); receptor activity (GO:0004872); signal transducer activity (GO:0004871); structural molecule activity (GO:0005198); and transporter activity (GO:0005215)