Fig. 3
From: Kinase domain activation through gene rearrangement in multiple myeloma
Expression of MAP3K14 and NTRK1 in newly diagnosed myeloma patient samples. a Spiked expression of probeset 205192_at on U133 Plus 2.0 arrays was used as a surrogate for the t(14;17). b Spiked expression of MAP3K14 in the CoMMpass RNA-seq dataset. c Spiked expression of NTRK1 in the CoMMpass RNA-seq dataset. Red and green circles indicate presence of an Ig or non-Ig translocation in the WGS data, respectively. Yellow circles are samples with a MAP3K14 or NTRK1 fusion gene in RNA-seq data. The solid gray line indicates the median expression of the probeset across all samples. The dotted gray line indicates the median plus 2 standard deviations and was used as the cutoff to determine spiked expression
