Table 2 Kinase fusion genes identified in the CoMMpass dataset
From: Kinase domain activation through gene rearrangement in multiple myeloma
Sample | Cytogenetic group | IMWG risk | Head gene | Head last exon | Tail gene | Tail first exon | In-frame |
|---|---|---|---|---|---|---|---|
MMRF_1032_1 | HRD | Standard | SND1 | 10 | BRAF | 11 | Yes |
MMRF_1232_4 | HRD | ND | TPR | 10 | NTRK1 | 3 | Yes |
MMRF_1331_1 | HRD | Standard | CDC27 | 4 | MAP3K14 | 4 | Yes |
MMRF_1392_1 | t(4;14) | High | FCHSD2 | 2 | MAP3K14 | 4 | Yes |
MMRF_1618_1 | t(14;16) | ND | NMT1 | 1 | MAP3K14 | 4 | Yes |
MMRF_1625_1 | t(14;20) | Standard | EFTUD2 | 11 | MAP3K14 | 3 | Yes |
MMRF_1656_1 | HRD | Standard | TPM3 | 6 | NTRK1 | 10 | Yes |
MMRF_1846_1 | t(11;14) | Standard | CREB1 | 1 | ALK | 9 | Yes |
MMRF_2000_1 | t(11;14) | Low | TAF15 | 3 | MAP3K14 | 6 | Yes |
MMRF_2272_1 | t(4;14) | High | YBX1 | 2 | MAP3K14 | 4 | Yes |
MMRF_2412_1 | HRD | Standard | IKZF3 | 1 | MAP3K14 | 4 | Yes |
MMRF_2490_1 | t(12;14) | Standard | ARHGEF2 | 21 | NTRK1 | 12 | Yes |
MMRF_1783_2 | t(4;14) | High | BRAF | 7 | AGK | 3 | Yes |
