Table 3 Multivariate logistic regression model for first TE grade ≥ 3 infection during the first 4 months of treatment (1369 patients included)

From: A predictive model for risk of early grade ≥ 3 infection in patients with multiple myeloma not eligible for transplant: analysis of the FIRST trial

Variable

Coefficienta

Odds ratio

P-value

Points

Infection risk

 

Estimate

SE

    

Sβ2M ≤ 3 mg/L

−0.812

0.353

0.44

0.021

−2

Low

ECOG PS of 0

−0.403

0.216

0.67

0.062

−1

Low

Hemoglobin ≤ 11 g/dL

0.366

0.207

1.44

0.077

1

High

ECOG PS of ≥ 2

0.457

0.189

1.58

0.016

1

High

LDH ≥ 200 U/L

0.552

0.186

1.74

0.003

1

High

Sβ2M ≥ 6 mg/L

0.820

0.176

2.27

 < 0.001

2

High

  1. ECOG PS Eastern Cooperative Oncology Group performance status, LDH lactate dehydrogenase, Sβ2M serum β2-microglobulin, TE treatment emergent
  2. a Coefficient in the multivariate logistic model
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