Fig. 3
From: Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML
Antigen Coexpression in AML and Normal Hematopoiesis. Antigen coexpression on primary AML cells and on normal hematopoietic cells of healthy donor-derived bone marrow (HD BM). Each dot indicates one independent sample measurement and the MFI ratios for the respective pair of antigens. Colors indicate different cell populations. Colored areas indicate density of dots. Black lines indicate MFI ratio of 1.5 as cutoff for positivity. Coexpression rate indicates the proportion of samples with antigen coexpression (MFI ratio > 1.5 for both antigens) in relation to all measured samples. a Suitable target antigen combinations. b Unsuitable target antigen combinations. c Target antigen combinations including CD7. d Summary of antigen coexpression data. Arrows indicate suitable target antigen combinations
