Fig. 2
From: Molecular pathogenesis of disease progression in MLL-rearranged AML
Whole exome sequencing (WES) of mouse MLL/AF9-AML. a, b Upper panels showed 12 and 13 mice analyzed by WES in strain A1 and B1, respectively. Middle panels demonstrated landscape of somatic mutations in each strain. Green and gray indicated shared and private mutations, respectively. Driver mutations were represented in bold italic font. In lower panels, fishplots displayed clonal architecture in A1-4-7 and B1-4-5 mice according to the results of mutational landscape in their own and their ancestry transplant generations. c–e Upper panels showed each 3 mice per strain from strain C1, C2, and E1, respectively. Lower panels demonstrated landscape of somatic mutations in each strain
