Table 2 List of 111 genes commonly mutated in AML and cancer screened using targeted NGS
From: Single cell analysis of clonal architecture in acute myeloid leukaemia
Symbol | Ensembl ID | NCBI | Position | Symbol | Ensembl ID | NCBI | Position | Symbol | Ensembl ID | NCBI | Position |
|---|---|---|---|---|---|---|---|---|---|---|---|
ABCA12 | ENSG00000144452 | 26154 | 2q34 | GATA2 | ENSG00000179348 | 2624 | 3q21.3 | NUP98 | ENSG00000110713 | 4928 | 11p15.4 |
ABL1 | ENSG00000097007 | 25 | 9q34.1 | GNAS | ENSG00000087460 | 2778 | 20q13.3 | OCA2 | ENSG00000104044 | 4948 | 15q12-q13.1 |
ACTR5 | ENSG00000101442 | 79913 | 20q11.23 | HIPK2 | ENSG00000064393 | 28996 | 7q34 | PDGFRA | ENSG00000134853 | 5156 | 4q12 |
ARHGAP26 | ENSG00000145819 | 23092 | 5q31 | HRAS | ENSG00000174775 | 3265 | 11p15.5 | PHF12 | ENSG00000109118 | 57649 | 17q11.2 |
ASXL1 | ENSG00000171456 | 171023 | 20q11.1 | HMGA2 | ENSG00000149948 | 8091 | 12q15 | PHF6 | ENSG00000156531 | 84295 | Xq26.2 |
ATRX | ENSG00000085224 | 546 | Xq21.1 | IDH1 | ENSG00000138413 | 3417 | 2q33.3 | PKP3 | ENSG00000184363 | 11187 | 11p15 |
ATXN7L1 | ENSG00000146776 | 222255 | 7q22.3 | IDH2 | ENSG00000182054 | 3418 | 15q26.1 | PRDX2 | ENSG00000167815 | 7001 | 19p13.2 |
BCOR | ENSG00000183337 | 54880 | Xp11.14 | IKZF1 | ENSG00000185811 | 10320 | 7p13 | PRPF40B | ENSG00000110844 | 25766 | 12q13.12 |
BRAF | ENSG00000157764 | 673 | 7q34 | INVS | ENSG00000119509 | 27130 | 9q31 | PTEN | ENSG00000171862 | 5728 | 10q23.3 |
CBL | ENSG00000110395 | 867 | 11q23.3 | IRF1 | ENSG00000125347 | 3659 | 5q31.1 | PTPN11 | ENSG00000179295 | 5781 | 12q24.1 |
CBLB | ENSG00000114423 | 868 | 3q13.11 | JAK2 | ENSG00000096968 | 3717 | 9p24 | RAD21 | ENSG00000164754 | 5885 | 8q24.11 |
CBLC | ENSG00000142273 | 23624 | 19q13.2 | JAK3 | ENSG00000105639 | 3718 | 19p13.1 | RAD50 | ENSG00000113522 | 10111 | 5q31.1 |
CD101 | ENSG00000134256 | 9398 | 1p13 | KDM2B | ENSG00000089094 | 84678 | 12q24.31 | RB1 | ENSG00000139687 | 5925 | 13q14 |
CDH1 | ENSG00000039068 | 999 | 16q22.1 | KDM5A | ENSG00000073614 | 5927 | 12p13.33 | RINT1 | ENSG00000135249 | 60561 | 7q22.3 |
CDKN1B | ENSG00000111276 | 1027 | 12p13.1 | KDM6A | ENSG00000147050 | 7403 | Xp11.2 | RORC | ENSG00000143365 | 6097 | 1q21 |
CDKN2A | ENSG00000147889 | 1029 | 9p21 | KIT | ENSG00000157404 | 3815 | 4q12 | RUNX1 | ENSG00000159216 | 861 | 21q22.3 |
CDKN2B | ENSG00000147883 | 1030 | 9p21.3 | KRAS | ENSG00000133703 | 3845 | 12p12.1 | RUNX1T1 | ENSG00000079102 | 862 | 8q22 |
CEBPA | ENSG00000245848 | 1050 | 19q13.1 | LCORL | ENSG00000178177 | 254251 | 4p15.31 | SF1 | ENSG00000168066 | 7536 | 11q13.1 |
CHGA | ENSG00000100604 | 1113 | 14q32 | LILRA3 | ENSG00000170866 | 11026 | 19q13.4 | SF3A1 | ENSG00000099995 | 10291 | 22q12.2 |
CREBBP | ENSG00000005339 | 1387 | 16p13.3 | MAP2K5 | ENSG00000137764 | 5607 | 15q23 | SF3B1 | ENSG00000115524 | 23451 | 2q33.1 |
CSF1R | ENSG00000182578 | 1436 | 5q32 | MET | ENSG00000105976 | 4233 | 7q31 | SH2B3 | ENSG00000111252 | 10019 | 12q24.12 |
CSF2 | ENSG00000164400 | 1437 | 5q31.1 | MLL | ENSG00000118058 | 4297 | 11q23 | SOCS1 | ENSG00000185338 | 8651 | 16p13.13 |
CTNNA1 | ENSG00000044115 | 1495 | 5q31 | MLL2 | ENSG00000167548 | 8085 | 12q12 | SPI1 | ENSG00000066336 | 6688 | 11p11.2 |
CUX1 | ENSG00000160967 | 1523 | 7q22.1 | MLL3 | ENSG00000055609 | 58508 | 7q36.1 | SRPK2 | ENSG00000135250 | 6733 | 7q22.3 |
DDX18 | ENSG00000088205 | 8886 | 2q14.1 | MLL5 | ENSG00000005483 | 55904 | 7q22.3 | SRSF2 | ENSG00000161547 | 6427 | 17q25.1 |
DNMT1 | ENSG00000130816 | 1786 | 19p13.2 | MMD2 | ENSG00000136297 | 221938 | 7p22.1 | STAG2 | ENSG00000101972 | 10735 | Xq25 |
DNMT3A | ENSG00000119772 | 1788 | 2p23 | MN1 | ENSG00000169184 | 4330 | 22q12.1 | STK17B | ENSG00000081320 | 9262 | 2q32.3 |
EGFR | ENSG00000146648 | 1956 | 7p12 | MPL | ENSG00000117400 | 4352 | 1p34.2 | TCF4 | ENSG00000196628 | 6925 | 18q21.2 |
ELF1 | ENSG00000120690 | 1997 | 13q14.11 | MTAP | ENSG00000099810 | 4507 | 9p21.3 | TET1 | ENSG00000138336 | 80312 | 10q21.3 |
EP300 | ENSG00000100393 | 2033 | 22q13 | MYC | ENSG00000136997 | 4609 | 8q24.21 | TET2 | ENSG00000168769 | 54790 | 4q24 |
ERG | ENSG00000157554 | 2078 | 21q22.2 | NF1 | ENSG00000196712 | 4763 | 17q11.2 | TP53 | ENSG00000141510 | 7157 | 17p13.1 |
ETV6 | ENSG00000139083 | 2120 | 12p13.2 | NLRP1 | ENSG00000091592 | 22861 | 17p13.2 | U2AF1 | ENSG00000160201 | 7307 | 21q22.3 |
MECOM | ENSG00000085276 | 2122 | 3q26 | NOTCH1 | ENSG00000148400 | 4851 | 9q34.3 | U2AF2 | ENSG00000063244 | 11338 | 19q13.42 |
EZH2 | ENSG00000106462 | 2146 | 7q35-36 | NPM1 | ENSG00000181163 | 4869 | 5q35 | WT1 | ENSG00000184937 | 7490 | 1p13 |
FAM175B | ENSG00000165660 | 23172 | 10q26.13 | NR5A1 | ENSG00000136931 | 2516 | 9q33 | ZEB2 | ENSG00000169554 | 9839 | 2q22.3 |
FBXW7 | ENSG00000109670 | 55294 | 4q31.3 | NRAS | ENSG00000213281 | 4893 | 1p13.2 | ZRSR2 | ENSG00000169249 | 8233 | Xp22.1 |
FLT3 | ENSG00000122025 | 2322 | 13q12 | NRD1 | ENSG00000078618 | 4898 | 1p32.2-p32.1 | ||||
GATA1 | ENSG00000102145 | 2623 | Xp11.23 | NSD1 | ENSG00000165671 | 64324 | 5q35.2 |
