Fig. 1 | Leukemia

Fig. 1

From: Molecularly distinct models of zebrafish Myc-induced B cell leukemia

Fig. 1

Gene expression differences define T- vs. B-lineages in ALL of both the rag2:mMyc and rag2:hMYC;lck:eGFP models. A. Principal component analysis of RNAseq expression profiles of previously-classified mMyc-induced T- (blue, n = 8), B- (red, n = 2), or biphenotypic ALL (pink, n = 1) compared with 13 unknown hMYC-induced ALL (black). B. Heatmap and hierarchical clustering using the top 100 positively- and negatively-correlated genes from PC2. B cell-specific genes are denoted in blue and T cell-specific genes in red at the right

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