Fig. 2
From: Molecularly distinct models of zebrafish Myc-induced B cell leukemia
Identification of two molecularly-distinct B-ALL types arising independently in either the ighm+ or ighz+ B cell lineages. A. T cell receptor beta and Ig heavy chain expression in individual ALLs. tcrβ recombination is denoted by grey-shaded boxes (left column), with percentage of GFPhi cells in each rag2:hMYC;lck:eGFP ALL noted in right column. Histograms depict expression of tcrβ and igh constant regions by each ALL. Not available (NA). B. Heatmap showing expression of genes differentially expressed in T-ALL, mMyc/ighm+ B-ALL, and hMYC/ighz+ B-ALL. C. Geneset enrichment analysis using genes positively correlated with each ALL molecular subtype. T-ALL (blue), mMyc/ighm+ B-ALL (red), and hMYC/ighz+ B-ALL (orange). Complete gene set and GSEAsig results are provided in Supp. Tables 3 and 4
