Fig. 4
Secretion of TGF-β1, GDF11, IL-10, and IL-1α during four weeks of NBM and MDS-RS 3D cultures. a Concentration of TGF-β1 in pg/ml measured at the end of week 1, 2, and 4 of 3D CD34+ (left) and MNC (right) 3D cultures (n = 3), with p = 0.048 for week 4 of MNC cultures. b Concentration of GDF11 in pg/ml measured at the end of week 1, 2, and 4 of 3D CD34+ (left) and MNC (right) 3D cultures (n = 3), with p < 0.001 for week 4 of MNC cultures. c Concentration of IL-10 in pg/ml measured at the end of week 1, 2, and 4 of 3D CD34+ (left) and MNC (right) 3D cultures (n = 3), with p = 0,001 for week one of MNC cultures. d Concentration of IL-1α in pg/ml measured at the end of week 1, 2, and 4 of 3D CD34+ (left) and MNC (right) 3D cultures (n = 3). The data is plotted as means ± SEM and an unpaired two-tailed t-tests was used for calculations
