Table 2 Baseline characteristics by frailty group

From: A simplified frailty scale predicts outcomes in transplant-ineligible patients with newly diagnosed multiple myeloma treated in the FIRST (MM-020) trial

Characteristic

Nonfrail (n = 828)

Frail (n = 790)

Age, n (%)

  Median (range), years

70 (40–80)

77 (44–92)

  <65 years

66 (8)

26 (3)

  65–75 years

754 (91)

299 (38)

  76–80 years

74 (9)

290 (37)

  >80 years

0

201 (25)

Sex, n (%)

  Male

436 (53)

415 (53)

  Female

392 (47)

375 (47)

ECOG performance status, n (%)a

  0

401 (48)

73 (9)

  1

427 (52)

368 (47)

  2

0

343 (43)

  3

0

6 (<1)

  Data not available

0

0

International Staging System stage, n (%)b

  I or II

575 (69)

419 (53)

  III

253 (31)

371 (47)

Lactate dehydrogenase, n (%)

  <200 U/L

707 (85)

612 (78)

  ≥200 U/L

120 (15)

177 (22)

 Missing data

1

1

Creatinine clearance, n (%)

  <60 mL/min

299 (36)

478 (61)

  <30 mL/min

38 (5)

108 (14)

  ≥60 mL/min

529 (64)

312 (39)

  1. ECOG Eastern Cooperative Oncology Group
  2. aECOG scores range from 0 to 5, with higher numbers indicating greater disability
  3. bHigher stages indicate more severe disease