Table 3 Patients’ disposition based on COVID-19 severity.

From: COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

Variable

Severe COVID-19 (n = 151)

Nonsevere COVID-19 (n = 39)

p

Age

 ≥65 years (%)

112 (74.2)

17 (43.6)

<0.05

 <65 years (%)

39 (25.8)

22 (56.4)

Gender

 Male (%)

98 (64.9)

28 (71.8)

n.s.

 Female (%)

53 (35.1)

11 (28.2)

Median time between CLL diagnosis and COVID-19

88

71

n.s.

Treatment for CLL

 Untreated (%)

64 (42.7)

9 (23.1)

<0.05

 Treated (%)

86 (57.3)

30 (76.9)

Treatment during the last 12 months or ongoing

 Yes (%)

60 (39.7)

24 (61.5)

<0.05

 Untreated or treated > 12 months before (%)

91 (60.3)

15 (38.5)

Treatment

 1 previous line (%)

48 (31.8)

14 (35.9)

n.s.

 2 or more previous lines (%)

38 (25.2)

16 (41.0)

Comorbidities

 >2

46 (30.5)

12 (30.8)

n.s.

 ≤2

105 (69.5)

27 (69.2)

Hypogammalobulinemia

 Yes

66 (55.0)

23 (67.6)

n.s.

 No

54 (45.0)

11 (32.4)

Outcome

 Alive (%)

96 (63.6)

37 (97.4)

<0.00001

 Dead (%)

55 (36.4)

1 (2.6)

  1. Bold values indicate statistical significance p < 0.05.