Table 3 Complications and therapy.

From: Cancer increases risk of in-hospital death from COVID-19 in persons <65 years and those not in complete remission

 

Total N = 1859

Non-cancer N = 1794

Cancer N = 65

P-value

Complications

 ARDS

227 (12)

208 (12)

19

<0.001

 Bacterial infections

563 (30)

533 (30)

30

0.005

 Septic shock

64 (4)

57 (4)

7

0.007

 Acute kidney injury

99 (5)

90 (5)

9

0.002

 Heart injury

229 (12)

215 (12)

14

0.021

 Abnormal LFT

456 (25)

440 (25)

16

0.984

 Gastro-intestinal bleeding

34 (2)

29 (2)

5

<0.001

 Coagulopathy

49 (3)

47 (3)

2

0.821

 Multiple organ failure

129 (7)

117 (7)

12

<0.001

Therapy

 Antibiotics

1559 (85)

1497 (85)

62

0.019

 Anti-fungal drugs

71 (4)

64 (4)

7

0.005

 Oseltamivir

757 (41)

729 (41)

28

0.697

 Umifenovir

1386 (75)

1343 (75)

43

0.110

 Lopinavir/ritonavir

339 (23)

328 (24)

11

0.357

 Interferon alpha

387 (21)

363 (20)

24

0.001

 Corticosteroids

753 (41)

725 (40)

28

0.670

 IVIG

506 (29)

478 (29)

28

0.009

 High-flow nasal cannula oxygen therapy

233 (16)

214 (15)

19

0.001

 Non-invasive mechanical ventilation

145 (8)

130 (7)

15

<0.001

 Invasive mechanical ventilation

85 (5)

78 (4)

7

0.015

 ECMO

4 (0.2)

4 (0.2)

0

>0.999

 CRRT

23 (1)

22 (1)

1

0.561

Outcomes

 Death

209 (11)

191 (11)

18

<0.001

 Time from illness onset to ICU admission, median (IQR), days

14 (10, 20)

14 (10, 20)

14 (7, 21)

0.790

 Time from illness onset to repeated negative SARS-CoV-2 tests, median (IQR), days

22 (17, 28)

22 (17, 28)

20 (16, 28)

0.379

 Time from illness onset to admission, median (IQR), days

10 (7, 15)

10 (7, 15)

10 (7, 13)

0.104

 Time from illness onset to progression, median (IQR), days

10 (7, 15)

10 (5, 14)

11 (6, 18)

0.284

 Time from illness onset to outcomea, median (IQR), days

30 (23, 37)

30 (23, 37)

28 (21, 35)

0.209

 Time from diagnosis to outcomea, median (IQR), days

19 (13, 27)

19 (13, 27)

21 (14, 27)

0.503

 Time from admission to outcomea, median (IQR), days

18 (12, 23)

18 (12, 23)

18 (13, 26)

0.353

  1. LFT liver function test, ARDS acute respiratory distress syndrome, IVIG intravenous immunoglobin, ECMO extra-corporeal membrane oxygenation, CRRT continuous renal replacement therapy, ICU intensive care unit.
  2. aOutcome refers to discharged alive or died.
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