Fig. 1: Overview of the transition and transversion types and the single base substitution (SBS) mutational signatures in the pediatric acute myeloid leukemias cases.

Left panel: the distribution of the six different transition and transversion types per case. Middle panel: heat map showing the distribution of the SBS signatures in each case. Right panel: The frequencies of the five overall most common signatures (SBS1, SBS18, SBS32, SBS37, and SBS39) per case.