Fig. 6: EVL is significantly overexpressed in lymphoid leukemia compared to healthy bone marrow and myeloid malignancies. | Leukemia

Fig. 6: EVL is significantly overexpressed in lymphoid leukemia compared to healthy bone marrow and myeloid malignancies.

From: The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision

Fig. 6

a Expression of EVL in 2096 patient samples with hematopoietic malignancies compared to healthy bone marrow (BM). AML acute myeloid leukemia, MDS myelodysplastic syndrome, CLL chronic lymphoid leukemia, ALL acute lymphoid leukemia. b Association of the expression level of EVL with immunoglobulin heavy chain gene (IGHV) mutation status in 120 CLL samples. M mutated, U unmutated. c Relative miR-342-3p expression identified by small RNA-seq in the indicated AML samples with normal karyotype compared to healthy bone marrow-derived mononuclear cells (BM MNC). FLT3 FMS-related tyrosine kinase 3, ITD internal tandem duplications, TKD tyrosine kinase domain. *P < 0.05; **P < 0.01; ***P < 0.001.

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