Fig. 1: Polygenic risk score distribution among controls, LC-MBL, HC-MBL, and CLL European ancestry and African-American individuals. | Leukemia

Fig. 1: Polygenic risk score distribution among controls, LC-MBL, HC-MBL, and CLL European ancestry and African-American individuals.

From: Polygenic risk score and risk of monoclonal B-cell lymphocytosis in caucasians and risk of chronic lymphocytic leukemia (CLL) in African Americans

Fig. 1

A Boxplots representing the CLL-PRS distribution among EA controls, LC-MBL, HC-MBL, and CLL. The white line in the box represents the median score of 7.46, 7.84, 8.05, and 8.24 for controls, LC-MBL, HC-MBL, and CLL, respectively. P value represents the statistical difference of the CLL-PRS between the four groups. B Boxplots representing the CLL-PRS distribution among AA controls and CLL. The white line in the box represents the median score of 7.25 and 7.53 for controls and CLL, respectively. P value represents the statistical difference between the CLL-PRS in AA controls and CLL. Y-axis (CLL-PRS) represents a weighted average across 41 CLL risk SNPs. AA African-American, CLL chronic lymphocytic leukemia, EA European Ancestry, HC high-count, LC low-count, MBL Monoclonal B-cell lymphocytosis, PRS polygenic risk score.

Back to article page