Table 1 Baseline characteristics in the intention-to-treat population (N = 16; all hospitalized and on invasive ventilation).

From: The janus-kinase inhibitor ruxolitinib in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)

 

N

Mean (±SD)

Median or freq.

Range or percentage

Age (yrs.)

16

59.5 (±14.92)

59

35–92

Sex, female/male (Pts./%)

16

 

3/13

18.75/81.25%

Weight (kg)

16

89.25 (±17.76)

90

60–127

Height (cm)

16

175.2 (±6.06)

175

163–186

BMI (kg/m2)

16

29.2 (±6.65)

28

22–47.8

Vital signs

 Heart rate (beats per minute)

16

77.1 (±17.1)

74.0

55–120

 Respiratory rate (breaths per minute)

16

16.8 (±5)

14.5

12–28

 PaO2/FiO2 (ratio)

16

167.3 (±148.7)

147.5

55–680

 Blood Pressure, systolic (mmHg)

16

109.8 (±13.2)

110.0

90–135

 Blood Pressure, diastolic (mmHg)

16

55.4 (±10.7)

55.0

40–80

 Temperature (°C)

16

36.8 (±1.3)

36

35–39.6

Risk factors

 

N Pts.

  

N Risk Factors

 Chronic liver disease

2

  

2

 Chronic lung disease

2

  

2

 Chronic nervous system disorder

3

  

3

 DNR status

1

  

1

 Diabetes

4

  

4

 Disorder of cardiovascular system

10

  

20

 Malignant neoplastic disease

2

  

2

 Respiratory therapy (before trial)

12

  

12

 Rheumatological/Immunological disease

4

  

7

 Smoking status (smoker/former smoker)

6

  

6

 Thromboembolic event

3

  

3