Table 2 CLL-directed treatment.

From: COVID-19 severity and mortality in patients with CLL: an update of the international ERIC and Campus CLL study

Treatment

Category

Number

Percentage

Missing

CLL treatment status

Treated

547

58.1%

0 (0%)

Untreated

394

41.9%

Treated status in last 12 months

Treated

432

46%

2 (0.2%)

Untreated

507

54%

Treatment status for CLL at the time of COVID-19

Treated

320

34%

1 (0.1%)

Untreated

620

66%

Management of CLL treatment

Continued as planned

104

32.7%

(0.6%)

Replaced with other

2

0.6%

Stopped

212

66.7%

Total prior lines of treatment

1

275

50.7%

5 (0.9%)

2

149

27.5%

3

60

11.1%

4

33

6.1%

>4

25

4.6%

Treatment at the time of COVID-19

BTKi

179

56.3%

2 (0.6%)

Venetoclax

34

10.7%

Venetoclax +Anti-CD20

17

5.3%

PI3K inhibitors

10

3.1%

PI3K inhibitors + Anti-CD20

3

0.9%

Anti-CD20

8

2.5%

Chemotherapy

22

6.9%

Chemoimmunotherapy

29

9.1%

BTKi + Venetoclax

7

2.2%

BTKi + Venetoclax + Anti-CD20

2

0.6%

Steroids only

7

2.2%

  1. PI3K Phosphatidylinositol-3 kinase, BTKi Bruton’s tyrosine kinase inhibitor.