Fig. 2: CXCL10 secreted and mRNA levels after miR-15a-5p mimic transfection. | Leukemia

Fig. 2: CXCL10 secreted and mRNA levels after miR-15a-5p mimic transfection.

From: MicroRNA-15a-5p acts as a tumor suppressor in histiocytosis by mediating CXCL10-ERK-LIN28a-let-7 axis

Fig. 2

A KG-1a (green), OCI-AML3 (red), and Ba/F3 cells overexpressing the BRAFV600E construct (blue), were transfected with a miR-15a-5p mimic (50 nM) or with a negative control for 48 h. The bars represent the expression of miR-15a-5p post-transfection as measured by qRT-PCR, normalized to snRNA U6 + SEM. B CXCL10 mRNA expression levels and (C) secreted expression levels were downregulated after transfection with a miR-15a-5p mimic in KG-1a, OCI-AML3, and Ba/F3V600E cells. *p < 0.05.

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