Table 2 Univariable analysis.
Patients | 90-day overall survival | ||||||
|---|---|---|---|---|---|---|---|
Patient characteristics | n = 112 | % | 95% CI | HR | 95% CI | P | |
Overall | 112 | 64.9 | 56.2–74.9 | ||||
Gender | 0.02 | ||||||
Female | 33 | 79.7 | 66.1–96.0 | 0.38 | 0.16–0.90 | ||
Male | 79 | 58.9 | 48.7–71.3 | 1 | |||
Age | 0.006 | ||||||
<70 years | 77 | 70.9 | 60.6–83.0 | 1 | |||
≥70 years | 35 | 50.2 | 36–70.2 | 2.41 | 1.26–4.60 | ||
High blood pressure | 0.003 | ||||||
Yes | 20 | 42.9 | 25.5–72 | 2.77 | 1.37–5.62 | ||
No | 92 | 69.5 | 60.2–80.3 | 1 | |||
Diabetes | 0.216 | ||||||
Yes | 7 | 42.9 | 18.2–100 | 1.93 | 0.68–5.44 | ||
No | 105 | 66.7 | 57.9–76.9 | 1 | |||
Body mass index | 0.05 | ||||||
<25 | 52 | 59.7 | 47.4–75.2 | 1 | |||
25–30 | 32 | 77.6 | 64.2–93.7 | 0.48 | 0.2–1.13 | ||
≥30 | 12 | 23.3 | 5.1–100 | 1.68 | 0.71–3.99 | ||
Missing data | 16 | 80.4 | 62.7–100 | 0.44 | 0.13–1.49 | ||
Hematological diseases | <0.0001 | ||||||
B-lymphoid neoplasm | 83 | 77.5 | 68.5–87.7 | 1 | |||
Myeloid neoplasm | 10 | 20.0 | 5.8–69.1 | 7.79 | 3.26–18.61 | ||
Plasma-cell neoplasm | 19 | 36.8 | 20.4–66.4 | 4.6 | 2.17–9.78 | ||
Previous anti-CD20/CD19 mAbs | <0.0001 | ||||||
Yes | 81 | 76.9 | 67.7–87.4 | 0.21 | 0.11–0.42 | ||
No | 31 | 35.5 | 22.1–57 | 1 | |||
Disease status | 0.8 | ||||||
Complete remission | 48 | 66.5 | 53.8–82.2 | 1 | |||
Partial remission/stable disease | 29 | 68.1 | 52.9–87.7 | 1 | 0.44–2.30 | ||
Progressive disease | 22 | 56.4 | 38.5–82.7 | 1.45 | 0.63–3.38 | ||
Missing data | 13 | 69.2 | 48.2–99.5 | 1 | 0.33–3.04 | ||
WHO scale (COVID-19 severity) | 0.0004 | ||||||
WHO 4 | 22 | 90 | 77.8–100 | 1 | |||
WHO 5 | 47 | 71.7 | 59.8–86 | 3.35 | 0.76–14.85 | ||
WHO 6 | 22 | 50 | 30.4–82.2 | 4.86 | 1.05–22.55 | ||
WHO 7 | 21 | 38.1 | 22.1–65.7 | 10.9 | 2.45–48.48 | ||
Steroid administration | 0.8 | ||||||
Yes | 72 | 63.7 | 53.2–76.3 | 1.12 | 0.56–2.23 | ||
No | 40 | 67.5 | 53.6–84.9 | 1 | |||
Time from COVID-19 onset to CCP | 0.002 | ||||||
<10 days | 29 | 43.4 | 28.3–66.8 | 1 | |||
>10 days | 83 | 72.8 | 63.3–83.6 | 0.37 | 0.20–0.72 | ||
