Table 15 Immunophenotypic diagnostic criteria of blastic plasmacytoid dendritic cell neoplasm.

From: The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms

Expected positive expression:

CD123*

TCF4*

TCL1*

CD303 *

CD304*

CD4

CD56

Expected negative markers:

CD3

CD14

CD19

CD34

Lysozyme

Myeloperoxidase

Immunophenotypic diagnostic criteria:

-Expression of CD123 and one other pDC marker(*) in addition to CD4 and/or CD56.

or,

-Expression of any three pDC markers and absent expression of all expected negative markers.

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