Fig. 2: Aetiology and recurrent genetic abnormalities in extranodal marginal zone lymphoma (EMZL) of various sites. | Leukemia

Fig. 2: Aetiology and recurrent genetic abnormalities in extranodal marginal zone lymphoma (EMZL) of various sites.

From: The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

Fig. 2

An important clinical application is that BIRC3::MALT1 identifies those cases of the gastric EMZL not responding to H. pylori eradication. As many of the genes involved in EMZL have not been uniformly investigated across different sites, only the recurrent genetic changes fundamental to the understanding of EMZL pathogenesis are presented. The height of the boxes under sites does not reflect the frequencies of these lymphomas. trans translocation, mut mutation, del: deletion.

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