Fig. 1: IGF2BP2 is highly expressed in T-ALL.
From: Inhibition of the m6A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia
A IGF2BP2 expression levels were analyzed among 14 human lymphoblastic leukemia cell lines in CCLE database (https://portals.broadinstitute.org/ccle). B IGF2BP2 expression levels in normal T cells (n = 17) and primary T-ALL patients cells (n = 13) from GEO database, GSE48558. C IGF2BP2 expression levels in T-ALL. IGF2BP2 mRNA expression levels (left) were analyzed in normal human bone marrow cells (n = 6) and primary T-ALL patients cells (n = 9) by RT-qPCR assays. IGF2BP2 protein expression levels (right) were assessed in normal human bone marrow cells (n = 3) and primary T-ALL patients cells (n = 3) by western blot. Data are mean ± SD values. *P < 0.05; **P < 0.01; ***P < 0.001.
